Rise in certain molecules may be responsible for bone aging

The aging body produces certain molecule – microRNA-141-3P – that inhibits bone cells from absorbing and incorporating vitamin C, touching off a degenerative cascade the weakens bones.

Work at the Medical College of Georgia at Augusta University has unmasked the culprit responsible for aging bones: the molecule microRNA-141-3P. According to exciting new research published in the Journals of Gerontology, this molecule controls the process of bone deterioration that occurs with age. Clinical trials have found that the molecule actively prevents bone cells from using vitamin C. It starves them of a vital nutrient needed to maintain strong, healthy bones. Without sufficient vitamin C, bone cells degrade and cease to multiply and repair bone tissue. The entire human skeleton suffers from the lack of vitamin C. Over time, diseases like osteoporosis develop.

To counter this negative process, scientists have administered an experimental microRNA-141-3P inhibitor in rodent subjects. Their findings are encouraging. The mouse and rat test subjects showed fewer signs of bone weakness and disease and maintained healthy skeletons far longer than their control group counterparts. The trials point to microRNA-141-3P inhibitors as effective anti-aging therapies.

While the commercial development and availability of this drug lies far in the future, researchers are optimistic. If successful, this newly developed therapy will ease the passage of time, allowing bodies to remain youthful and resilient.

Melanoma Decrease with Sunscreen

According to The American Cancer Society, the average time of diagnosis of individuals with melanoma is 63. However, melanoma isn’t that rare even among younger individuals. Truth be told, it’s not uncommon even in young adults (particularly young ladies).
A recent study conducted by the University of Sydney evaluated individuals between the ages of 18 and 40 who are regular users of sunscreen in their childhood. They found that their risk of reducing melanoma decreased by 40% when compared to individuals who rarely used sunscreen. This Research indicates that the regular use of sunscreen during childhood decreases the incidence of melanoma when these people mature.

Caroline G. Watts, Martin Drummond, Chris Goumas, Helen Schmid, Bruce K. Armstrong, Joanne F. Aitken, Mark A. Jenkins, Graham G. Giles, John L. Hopper, Graham J. Mann, Anne E. Cust. Sunscreen Use and Melanoma Risk Among Young Australian AdultsJAMA Dermatology, 2018; DOI: 10.1001/jamadermatol.2018.1774

Botulinum protein for other uses besides wrinkles

12 Jul 2018 Botox

The American Academy of Neurology guideline published in the April 18, 2016, online issue of Neurology® has several uses for botulinum toxin. It provides guidelines on the use of botulinum toxin for spasticity, cervical dystonia, blepharospasm and migraine headache, based on recent research. The protein is commonly used to relax muscles and soften the appearance of skin wrinkles in aesthetic medicine. Botox ® is a very popular form of this botulinum protein.

Dry Skin and Wrinkles

As moisture in the outer skin level drops, this external layer – the stratum corneum – progresses toward becoming dryer and stiffer. At the point when this happens, the small scale wrinkles at the surface of the skin, incited by facial muscle activities like grinning, turn out to be considerably more profound, bigger and, along these lines, more noticeable. A good moisturizing regiment and medical treatments such as Botox and microneedling can help this.


Raw Fruits and Vegetables for a Healthy Outlook

Eating raw fruits and vegetables may provide a mental boost. According to University of Otago researchers, cooking your fruits and vegetables may diminish some of  the nutrient content available for you to metabolize. The nutrients in some of the foods in their raw form were shown to have a positive effect on factors such as sleep patterns and the feeling of wellbeing.


Dr Cummings at Illinois State Medical Society

Dr A.J. Cummings has been attending the Illinois State Medical Society (ISMS), House of Delegates meeting for many years. This years meeting was this past weekend in Oak Brook. Here is where members meet to discuss Illinois State health policy and public health issues. A recurrent theme is assuring patients have good access to care and to help make the public aware of health issues. It is also a time for the physicians to interact and socialize. The various County Medical Societies make us the ISMS. The Peoria Medical Society, in which Dr Cummings has been president of twice, was established in 1848.

Dr AJ Cummings at conference

Dr Cummings had an opportunity this weekend to speak with several people regarding their aesthetic questions. At the top of the list was wrinkle concerns. Many treatment options are available to address wrinkles and a consultation can help develop determine the best course of action. Botox and microneedling are two options that are safe and cost effective.

Botox dosing adjustment

28 Mar 2018 Botox

According to Medscape.com the average amount of Botox (botulinumtoxinA) given can vary between clients. To soften Glabellar lines (number 11 lines between the eyebrows): give a total dose of 20 units. To treat Forehead lines: 20 units. To relax Canthal lines (Crow’s Feet): administer a total of 24 units (12 units per side). They go on to recommend considering adjusting the dose if no prior botulinum toxin treatment or based on client’s response. Our office routinely does this as we want our clients to have natural, beautiful looking results.

Dr Cummings Microneedling

14 Nov 2017 Microneedling

Dr Cummings has extensive experience with microneedling. This stimulates collagen and elastin production to produce lasting and natural results.

Visit with Dean of Medical School

19 Oct 2017 Uncategorized

Dr Cummings had the privilege of hosting the President of the Illinois State Medical Society as he visited the Peoria area. One of the meeting he had was a tour of the UICOMP Medical School by the Dean, Dr Sara Rusch. Ongoing research into cancer was emphasized along with updated teaching facilities for the medical students.

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